Search on: REGION, IMMUNOGLOBULIN HYPERVARIABLE 
Descriptors Found: 1
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Descriptor English:   Complementarity Determining Regions 
Descriptor Spanish:   Regiones Determinantes de Complementariedad 
Descriptor Portuguese:   Regiões Determinantes de Complementaridade 
Synonyms English:   Complementarity Determining Region
Complementarity Determining Region 1
Complementarity Determining Region 2
Complementarity Determining Region 3
Complementarity Determining Region I
Complementarity Determining Region II
Complementarity Determining Region III
Complementarity-Determining Region
Complementarity-Determining Region 3
Complementarity-Determining Region 3s
Complementarity-Determining Region, Third
Complementarity-Determining Regions
Complementarity-Determining Regions, Third
Hypervariable Region, Immunoglobulin
Hypervariable Regions, Immunoglobulin
Immunoglobulin Hypervariable Region
Immunoglobulin Hypervariable Regions
Region, Complementarity Determining
Region, Immunoglobulin Hypervariable
Regions, Complementarity Determining
Regions, Complementarity-Determining
Regions, Immunoglobulin Hypervariable
Third Complementarity Determining Region
Third Complementarity-Determining Region
Third Complementarity-Determining Regions  
Tree Number:   D12.644.541.500.650.500.180
D12.776.124.486.485.680.650.500.180
D12.776.124.486.485.797.180
D12.776.124.790.651.680.650.500.180
D12.776.124.790.651.797.180
D12.776.377.715.548.680.650.500.180
D12.776.377.715.548.797.180
D12.776.543.750.705.816.824.300
G02.111.570.060.425.160
Definition English:   Three regions (CDR1; CDR2 and CDR3) of amino acid sequence in the IMMUNOGLOBULIN VARIABLE REGION that are highly divergent. Together the CDRs from the light and heavy immunoglobulin chains form a surface that is complementary to the antigen. These regions are also present in other members of the immunoglobulin superfamily, for example, T-cell receptors (RECEPTORS, ANTIGEN, T-CELL). 
See Related English:   Receptors, Antigen, T-Cell
 
History Note English:   2001; for COMPLEMENTARITY DETERMINING REGION and HYPERVARIABLE REGION use IMMUNOGLOBULIN VARIABLE REGION 1988-2000 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis BI biosynthesis
BL blood CF cerebrospinal fluid
CH chemistry CL classification
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PD pharmacology
PH physiology PO poisoning
RE radiation effects TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   35339 
Unique Identifier:   D022801 

Occurrence in VHL: 		 

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DeCS